We stayed at the Anna during an extended layover in Munich at the start of our vacation. We chose this property primarily for its convenient location, in between the Hauptbahnhof and Karlsplatz. My husband and I had been to Munich before but my mother, who was traveling with us, had not, and since we had only a few days, we wanted to minimize time spent in transit.
This hotel is somewhat pricey, but we have found that most hotels in Munich are, due to the large numbers of business travelers. All hotels dramatically raise their rates any time there is a trade convention occurring, which seems to be most of the time. The Anna's rates were on par with most other similar properties.
The decor was the other reason we chose the Anna over some of the other hotels. The style is somewhat minimalist, but the rooms have all the amenities that one would expect. The bathrooms are really the highlight, with large shower stalls that have fun colored LED accent lighting. If you equate overstuffed chairs and chintz wallpaper with luxury, this might not be the best property for you. I did not notice any noise issues, but we were on the 5th floor. Also, my mom's single room was nearly as large, and just as nice as our double room, so this is worth considering if you are planning to travel alone. The breakfast buffet was more than adequate, and hot items can be ordered as well.

I am surprised about some of the positiv reports. I stayed for three nights, first night on Business and the rest for Leisure. On arrival the taxi driver dropped us in the rain 50 meters from the hotel as no cars allowed further. No porter employed so you have to look after your own things...one receptionist by check in - she took two reservations at the same time by phone and we waited 10 minutes before beeing checked in - the room was large but not as nice than the pictures on the website. The room was very loud too - located towards the tram line - breakfast was ok but nothing special.
The website looks very nice but really none of the pictures is the "real thing"...

My room at the Anna was booked for me by business partners whom I was visiting for a meeting in town. Overall instant reaction: a super place with slight noise problems on one side (so ask for a room on the other). More info:

My room was spotlessly clean and very elegant in a minimalist European way: accent spotlighting, very comfortable bed with twin duvets, hardwood floor and Venetian blinds (people with allergies or problems with carpets and drapes, this is the place for you). Free minibar in the non-spiritous mode (beers and soft drinks). Open closet area with decent removable hangers and good shelf space. Large flat-panel TV with all the usual German channels, as well as CNN, BBC 24, MTV, some other international favorites. The radio / sound system comes with a cable and plug so that you can plug in your iPod or other MP3 player and enjoy your own music. Air condtioning is quiet and effective.

Bathroom very neat -- textured slate floor, iridescent mosaics in the shower stall, which was a beautiful tall clear glass box. This featured a wide-rose "drench" shower head as well as the more typically European "telephone" hand-held shower fixture, and a graceful mosaicked seat built into the shower wall. High-style bowl sink on thick glass slab base -- very chic.

Someone in the comments complained about the lack of toiletries. The shower featured a tube of a combination body / hair shampoo, which is something you run into a lot in Germany. Then there was soap for the sink, as well as a little box with condoms and a nail-grooming kit. So if you need serious hair or body toiletries, you'd better bring your own.

About the noise: First of all, the rooms are acoustically bright because of the hardwood floor and lack of drapes, but this didn't particularly bother me. The other problem: the rooms on the road / tram side of the hotel start getting a little noisy around 6 AM. If noise is an issue for you, ask for a room on the side of the hotel that faces toward the pedestrian precinct.

Staff were beautifully polite, friendly, helpful, interested in knowing your name and pronouncing it correctly, and all English-fluent (for those who're nervous about the language divide). Service in the downstairs bar -- famous for its "environmental" light show, almost an art installation -- spills out into the street in good weather. Free wi-fi in the bar, which becomes a very convenient place to work: open, airy and pleasant. (This is also the breakfast room in the mornings.)

To sum up: a super place, one I look forward to visiting again when next in Munich.

I stay with my wife for 3 days and the position of the hotel was very helpful. Two minutes to the central train & sub station. Very clean and very quiet hotel. Free wireless internet access and free mini bar !!!